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Pathophysiology of Type 2 Diabetes Mellitus: A Comprehensive Analysis

Introduction

Type 2 diabetes mellitus (T2DM) represents a complex metabolic disorder characterized by insulin resistance and relative insulin deficiency. This pathophysiological analysis examines the cellular mechanisms underlying T2DM development, progression, and its clinical manifestations in adult populations...

Cellular Pathophysiology

The pathogenesis of T2DM involves multiple interconnected mechanisms at the cellular level. Insulin resistance, primarily occurring in skeletal muscle, adipose tissue, and hepatic cells, represents the initial pathophysiological event (American Diabetes Association, 2023)...
[Sample continues for 8 more pages with detailed analysis, evidence-based citations, and professional formatting]

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